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IFN-B 1A HUMAN

Synonyms:
Leukocyte interferon, B cell interferon, Type I interferon, IFNB1, IFB, IFF, IFNB,IFN-b 1a ,MGC96956.

Introduction:
Interferon-beta 1b has antiviral, antibacterial and anticancer activities.

Description:
Interferon-beta 1a Human Recombinant produced in CHO (Chinese Hamster Ovarian) cells is a single, glycosylated polypeptide chain containing 166 amino acids and having a molecular mass of 22500 Dalton.
IFN-beta1a is purified by proprietary chromatographic techniques.

Source:
CHO (Chinese Hamster Ovarian) cells.

Formulation:
Lyophilized from 1mg/ml solution containing 91 mg Human Albumin, and 620mg mannitol, and 9 mg Sodium Acetate.

Solubility:
It is recommended to reconstitute the lyophilized Interferon beta 1a in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability:
Lyophilized Interferon-beta 1a although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-Beta1a should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.

Purity:
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Amino acid sequence:
The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Tyr-Asn-Leu-Leu.

Biological Activity:
The specific activity as determined in a viral resistance assay (human “Wish” cell line and VSV virus or the monkey VERO cell line with EMCV virus) was found to be 270 x 10IU/mg.

Usage:
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Size :
10ug


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