Pro Bone Morphogenetic Protein -2 Human Recombinant is the precursor of BMP-2 which has 3 intramolecular cystein bridges is a homodimer, non-glycosylated, polypeptide chain containing 377 amino acids and having a molecular mass of 85,476 Dalton.
Pro Bone Morphogenetic Protein 2 is purified by proprietary chromatographic techniques.
Sterile Filtered White lyophilized (freeze-dried) powder.
The Pro Bone Morphogenetic Protein -2 Human Recombinant was lyophilized in 0.1M K-HEPES pH 7.0 / Mannite.
It is recommended to reconstitute the lyophilized Pro Bone Morphogenetic Protein -2 Human Recombinant in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Lyophilized Pro Bone Morphogenetic Protein -2 Human Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Pro Bone Morphogenetic Protein -2 Human Recombinant should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
The ProBMP-2 Human Recombinant administration leads to ectopic bone formation ion rats (Hillger et al., 2005).
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY.They may not be used as drugs,agricultural or pesticidal products, food additives or household chemicals.