Induced pluripotent stem (iPS) cells can be generated from differentiated somatic cells by over-expressing a set of specific transcription factors called reprogramming factors. Typically four reprogramming factors are chosen, Oct4, Sox2, Klf4 and c-Myc (OSKM), which are introduced into the target cells through genetic transduction using retroviral or lentiviral vectors. This product packages all four genes (OSKM) in one lentiviral vector. 

Titer (approx): 1 x 108 TU/ml
Vector Information: Vector includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE)
Promoter for Target Gene: CMV
Target Gene / Reporter(s): OCT4, SOX2, KLF4, C-MYC
Selection Gene: Puromycin
Biosafety Level: BSL-2
Shipped: Dry ice
Storage: Store at -80°C

Copyright © egfie Herndon, VA