SRY (sex determining region Y)-box 2 (SOX2) is a transcription factor critical for maintaining the self-renewal capacity of undifferentiated stem cells. Ectopic expression of SOX2 has been used to produce iPS cells in culture.
Virus:
CMV-SOX2
Titer (approx):
1 x 108 CFU/ml
Vector Information:
Vector includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE)