Purmorphamine

Chemical Name: 9-cyclohexyl-N-[4-(morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine

Molecular Weight: 520.62

Description: Purmorphamine is a 2,6,9-trisubstituted purine that promotes the differentiation of both human and mouse mesenchymal progenitor cells into osteoblasts. Purmorphamine can also be used to replace sonic hedgehog for the generation of motor neurons from human embryonic stem cells

Chemical structure:

Molecular formula: C₃₁H₃₂N₆O₂

CAS Number: 483367-10-8

Purity: ≥98% by HPLC

Storage: -20^oC

Solubility: Soluble in DMSO

References:
Wu et al (2002) A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells. J.Am.Chem.Soc. 124 14520.
Li et al (2008) Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules. Stem Cells 26: 886-893.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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