SB431542

Chemical Name: 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide

Molecular Weight: 384.4

Description: SB431542 is potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor activin receptor-like kinase ALK5 and its relatives ALK4 and ALK7. SB431542 does not inhibit kinases that are activated in response to serum or stress such as ERK, p38 or JNK.

Chemical structure:

Molecular formula: C₂₂H₁₆N₄O₃

CAS Number: 301836-41-9

Purity: ≥99% by HPLC

Storage: -20^oC

Solubility: Soluble in DMSO

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