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Veliparib(ABT-888)
Chemical Name: 1-[3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one

Molecular Weight: 244.3

Description:  a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively.

Chemical structure: 


Molecular formula: C13H16N4O

CAS Number: 912444-00-9

Purity: ≥99% by HPLC

Storage: -20oC

Solubility: Soluble in DMSO
 
References:

Shelton et al (2013) In vitro and in vivo enhancement of chemoradiation using the oral PARP inhibitor ABT-888 in colorectal cancer cells. Int J Radiat Oncol Biol Phys. 2013 Jul 1;86(3):469-76.

 
 For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.


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