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IOX2
Chemical Name: N-[[1,2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]-glycine

Molecular Weight: 352.34

Description:  IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM, >100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH.

Chemical structure: 


Molecular formula: C19H16N2O5
CAS Number: 931398-72-0
Purity: ≥99% by HPLC
Storage: -20oC
Solubility: Soluble in DMSO
 
References:

Sen et al. MicroRNA-138 regulates hypoxia-induced endothelial cell dysfunction by targeting S100A1. PLoS One. 2013 Nov 11;8(11)

 
 
 For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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