Romidepsin(FK228, Depsipeptide), 1mg

Chemical Name: Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl] cyclic (35)-disulfide

Molecular Weight: 540.70

Description: Romidepsin (FK228, depsipeptide) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively

Chemical structure:

Molecular formula: C24H36N4O6S2

CAS Number: 128517-07-7

Purity: ≥98% by HPLC

Storage: -20^oC

Solubility: Soluble in DMSO

References:
Sager et al. Electrocardiographic effects of class 1 selective histone deacetylase inhibitor romidepsin. Cancer Med. 2015 Apr 27. doi: 10.1002
Sodji et al. Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acids. Eur J Med Chem. 2015 Apr 8;96:340-359.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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