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OCT3/4 (POU5F1) is a transcription factor that is expressed in stem cells and germ cells. Its expression is required to sustain cell self-renewal of undifferentiated stem cells. Oct-3/4 is the most recognized marker for totipotent ES cells. Ectopic expression of OCT3/4 has been used to produce iPS cells in culture.
| Virus: | Inducible tet-on OCT3/4 |
| Titer (approx): | 1 x 108 CFU/ml |
| Vector Information: | Vector includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) |
| Promoter for Target Gene: | TRE |
| Target Gene / Reporter(s): | OCT3/4 |
| Selection Gene: | Puromycin |
| Biosafety Level: | BSL-2 |
| Shipped: | Dry ice |
| Storage: | Store at -80°C |
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