Krueppel-like factor 4 (KLF4) is a zinc finger transcriptional regulator that has been identified as a good indicator of stem cell-like capacity and is subsequently used in iPS cell generation. KFL4 plays an important role in maintaining stem cells, and in preventing their differentiation. This lentivirus expresses KLF4 under the control of the Tet promoter.

Virus: Inducible tet-on KLF4
Titer (approx): 1 x 108 CFU/ml
Vector Information: Vector includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE)
Promoter for Target Gene: TRE
Target Gene / Reporter(s): KLF4
Selection Gene: Puromycin
Biosafety Level: BSL-2
Shipped: Dry ice
Storage: Store at -80°C

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