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The miR-200 family (miR-200a, -200b, -200c, -141 and -429) and miR-205 are frequently silenced in advanced cancer and have been implicated in epithelial to mesenchymal transition (EMT) and tumor invasion by targeting the transcriptional repressors of E-cadherin, ZEB1 and ZEB2.
| Virus: | Inducible tet-on miR-200b,a, 429 |
| Titer (approx): | 1 x 108 CFU/ml |
| Vector Information: | Vector includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) |
| Promoter for Target Gene: | TRE |
| Target Gene / Reporter(s): | miR-200b,a, 429 |
| Selection Gene: | Puromycin |
| Biosafety Level: | BSL-2 |
| Shipped: | Dry ice |
| Storage: | Store at -80°C |
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| Items: | 0 |
| Subtotal: | $0.00 |
Note: All prices in US Dollars
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