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Microphthalmia-associated transcription factor (Mitf) is a member of the basic/helix-loop-helix/leucine zipper (b-HLH-ZIP) transcription factor subfamily. Mitf regulates the differentiation of melanocytes, optic cup-derived retinal pigment epithelium (RPE), and some types of bone marrow-derived cells. Mitf is crucial for normal retina and RPE development. This lentivirus expresses one of the isoform of Mitf, human Mitf-D, under the control of the Tet promoter.
| Virus: | Inducible tet-on Mitf-D lentivirus |
| Titer (approx): | 1 x 108 CFU/ml |
| Vector Information: | Vector includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) |
| Promoter for Target Gene: | TRE |
| Target Gene / Reporter(s): | Mitf-D |
| Selection Gene: | Puromycin |
| Biosafety Level: | BSL-2 |
| Shipped: | Dry ice |
| Storage: | Store at -80°C |
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| Subtotal: | $0.00 |
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