Microphthalmia-associated transcription factor (Mitf) is a member of the basic/helix-loop-helix/leucine zipper (b-HLH-ZIP) transcription factor subfamily. Mitf regulates the differentiation of melanocytes, optic cup-derived retinal pigment epithelium (RPE), and some types of bone marrow-derived cells. Mitf is crucial for normal retina and RPE development. This lentivirus expresses one of the isoform of Mitf, human Mitf-D, under the control of the Tet promoter.
||Inducible tet-on Mitf-D lentivirus
||1 x 108 CFU/ml
||Vector includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE)
|Promoter for Target Gene:
|Target Gene / Reporter(s):
||Store at -80°C