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Inducible tet-on NR2E3 lentivirus

NR2E3, a photoreceptor-specific orphan nuclear receptor, is believed to play a pivotal role in the differentiation of photoreceptors. Mutations in NR2E3 result in syndromes characterized by excess blue cones and loss 
of rods: enhanced S-cone syndrome (ESCS). 
This lentivirus expresses human NR2E3 under the control of the Tet promoter.

Virus: Inducible tet-on NR2E3
Titer (approx): 1 x 108 CFU/ml
Vector Information: Vector includes both 5’ and 3’ lentiviral LTR and all necessary elements for effective transduction; woodchuck hepatitis virus posttranscriptional regulatory element (WPRE)
Promoter for Target Gene: TRE
Target Gene / Reporter(s): NR2E3
Selection Gene: Puromycin
Biosafety Level: BSL-2
Shipped: Dry ice
Storage: Store at -80°C


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